Methanol → 3-Amino-N-(2-[(2,3-difluorobenzyl)thio]-6-methoxypyrimidin-4-yl)azetidine-1-sulfonamide
Reaction equation
[CH3:42][OH:43].[F:1][c:2]1[c:3]([CH2:4][S:5][c:6]2[n:7][c:8]([O:28][CH3:29])[cH:9][c:10]([NH:12][S:13](=[O:14])(=[O:15])[N:16]3[CH2:17][CH:18]([NH:20][C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:19]3)[n:11]2)[cH:30][cH:31][cH:32][c:33]1[F:34].[F:35][C:36]([F:37])([F:38])[C:39]([OH:40])=[O:41]>>[F:1][c:2]1[c:3]([CH2:4][S:5][c:6]2[n:7][c:8]([O:28][CH3:29])[cH:9][c:10]([NH:12][S:13](=[O:14])(=[O:15])[N:16]3[CH2:17][CH:18]([NH2:20])[CH2:19]3)[n:11]2)[cH:30][cH:31][cH:32][c:33]1[F:34]Participants
4
Sources & evidence
- ORD record
- ord-d05e5a02caa5470c916a1da40ef62618
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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