Hydrochloric Acid → [5-Bromo-4-(7-chlorobenzo[b]thiophen-2-yl)-pyrimidin-2-yl]-[3-(4-methyl-piperazin-1-yl)-propyl]-amine

HRID 836161Notes

Reaction equation

HRID 836161 reaction equation
[Br:4][c:5]1[c:6](-[c:22]2[cH:23][c:24]3[c:25]([s:26]2)[c:27]([O:31][CH3:32])[cH:28][cH:29][cH:30]3)[n:7][c:8]([NH:11][CH2:12][CH2:13][CH2:14][N:15]2[CH2:16][CH2:17][N:18]([CH3:21])[CH2:19][CH2:20]2)[n:9][cH:10]1.[Cl:33][c:34]1[c:35]2[s:36][cH:37][cH:38][c:39]2[cH:40][cH:41][cH:42]1.[ClH:1].[ClH:2].[ClH:3]>>[Br:4][c:5]1[c:6](-[c:22]2[cH:23][c:24]3[c:25]([s:26]2)[c:27]([Cl:33])[cH:28][cH:29][cH:30]3)[n:7][c:8]([NH:11][CH2:12][CH2:13][CH2:14][N:15]2[CH2:16][CH2:17][N:18]([CH3:21])[CH2:19][CH2:20]2)[n:9][cH:10]1

Participants

4

Reactant 3

HCID 313Hydrochloric Acid3×HCID 110628127-Chloro-1-benzothiopheneHCID 688569395-bromo-4-(7-methoxy-1-benzothiophen-2-yl)-N-[3-(4-methylpiperazin-1-yl)propyl]pyrimidin-2-amine

Product 1

HCID 68856038[5-Bromo-4-(7-chlorobenzo[b]thiophen-2-yl)-pyrimidin-2-yl]-[3-(4-methyl-piperazin-1-yl)-propyl]-amine

Sources & evidence

ORD record
ord-d0056e95dbe64ae0bbe2c18e49eac956
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…