Isopropanol → 2-[5-Bromo-2-(1-ethyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-8-ylamino)-pyrimidin-4-ylamino]-3-fluoro-N-methyl-benzamide
Reaction equation
[Br:16][c:17]1[c:18]([NH:24][c:25]2[c:26]([C:27](=[O:28])[NH:29][CH3:30])[cH:31][cH:32][cH:33][c:34]2[F:35])[n:19][c:20]([Cl:23])[n:21][cH:22]1.[CH:36]([OH:37])([CH3:38])[CH3:39].[NH2:1][c:2]1[cH:3][c:4]2[c:5]([cH:14][cH:15]1)[CH2:6][CH2:7][CH2:8][C:9](=[O:13])[N:10]2[CH2:11][CH3:12]>>[NH:1]([c:2]1[cH:3][c:4]2[c:5]([cH:14][cH:15]1)[CH2:6][CH2:7][CH2:8][C:9](=[O:13])[N:10]2[CH2:11][CH3:12])[c:20]1[n:19][c:18]([NH:24][c:25]2[c:26]([C:27](=[O:28])[NH:29][CH3:30])[cH:31][cH:32][cH:33][c:34]2[F:35])[c:17]([Br:16])[cH:22][n:21]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-5ecfcf2bd33649bc964bbf75c2c467c7
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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