Potassium Cation → tert-butyl 4-(5-chloro-1H-indol-3-yl)-5,6-dihydropyridine-1(2H)-carboxylate

HRID 836374Notes

Reaction equation

HRID 836374 reaction equation
[CH3:28][OH:29].[Cl:1][c:2]1[cH:3][c:4]2[cH:5][cH:6][nH:7][c:8]2[cH:9][cH:10]1.[K+:26].[O:11]=[C:12]1[CH2:13][CH2:14][N:15]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:16][CH2:17]1.[OH-:25].[OH2:27]>>[Cl:1][c:2]1[cH:3][c:4]2[c:5]([C:12]3=[CH:13][CH2:14][N:15]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:16][CH2:17]3)[cH:6][nH:7][c:8]2[cH:9][cH:10]1

Participants

7

Reactant 6

HCID 813Potassium CationHCID 887MethanolHCID 961HydroxideHCID 962WaterHCID 871105-ChloroindoleHCID 735900tert-Butyl 4-oxopiperidine-1-carboxylate

Product 1

HCID 12072032tert-butyl 4-(5-chloro-1H-indol-3-yl)-5,6-dihydropyridine-1(2H)-carboxylate

Sources & evidence

ORD record
ord-71980f5656b24611967049687fb8e89f
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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