Dimethylformamide → 4-Chloro-7-isopropyl-7H-pyrrolo[2,3-D]pyrimidine

HRID 836429Notes

Reaction equation

HRID 836429 reaction equation
[C:1](=[O:2])([O-:3])[O-:4].[Cl:7][c:8]1[c:9]2[c:10]([n:11][cH:12][n:13]1)[nH:14][cH:15][cH:16]2.[Cs+:5].[Cs+:6].[I:17][CH:18]([CH3:19])[CH3:20].[O:21]=[CH:22][N:23]([CH3:24])[CH3:25]>>[Cl:7][c:8]1[c:9]2[c:10]([n:11][cH:12][n:13]1)[n:14]([CH:18]([CH3:19])[CH3:20])[cH:15][cH:16]2

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 6362Isopropyl iodideHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 53566827H-Pyrrolo(2,3-d)pyrimidine, 4-chloro-

Product 1

HCID 722073574-Chloro-7-isopropyl-7H-pyrrolo[2,3-D]pyrimidine

Sources & evidence

ORD record
ord-a661d582c6a6404caa35434a619c5152
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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