4-Iodobenzoic acid → 4-[3-(3-Tert-butyl-5-chloro-4-dimethylaminophenyl)-3-hydroxyprop-1-ynyl]benzoic acid
Reaction equation
[C:11]([CH3:12])([CH3:13])([CH3:14])[c:15]1[cH:16][c:17]([CH:25]([C:26]#[CH:27])[OH:28])[cH:18][c:19]([Cl:24])[c:20]1[N:21]([CH3:22])[CH3:23].[Cu:29]([I:30])[I:31].[I:1][c:2]1[cH:3][cH:4][c:5]([C:6](=[O:7])[OH:8])[cH:9][cH:10]1>>[c:2]1([C:27]#[C:26][CH:25]([c:17]2[cH:16][c:15]([C:11]([CH3:12])([CH3:13])[CH3:14])[c:20]([N:21]([CH3:22])[CH3:23])[c:19]([Cl:24])[cH:18]2)[OH:28])[cH:3][cH:4][c:5]([C:6](=[O:7])[OH:8])[cH:9][cH:10]1Participants
4
Sources & evidence
- ORD record
- ord-c69543be966546348097f6947867e3a9
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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