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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 836576Generated: October 31, 2026

Hydrochloric Acid → 3-(3,5-Difluorophenoxy)-5-(1,3-dioxolan-2-yl)-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-indazole

https://huagongshe.com/reaction/836576

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantN,N-DimethylglycineHCID 673—
ReactantCarbonate IonHCID 19660—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
Reactant1,4-DioxaneHCID 31275—
Reactant3,5-DifluorophenolHCID 75928—
ReactantCesium cationHCID 104967—
Reactant5-(1,3-Dioxolan-2-yl)-3-iodo-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-indazoleHCID 58407604—
Product3-(3,5-Difluorophenoxy)-5-(1,3-dioxolan-2-yl)-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-indazoleHCID 58407629—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-69bb7e4cb33d486ebcfe9b3841818f52
Source noteTest data from https://doi.org/10.1039/C8SC04228D