Bromide ion → 6-Bromo-1-cyclopropyl-4,4-dimethyl-1,2,3,4-tetrahydroquinoline

HRID 836691Notes

Reaction equation

HRID 836691 reaction equation
[Br-:16].[Br:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[N:8]([CH:12]=[O:13])[CH2:7][CH2:6][C:5]2([CH3:14])[CH3:15].[CH2:17]([CH3:18])[Mg+:19].[CH3:20][CH2:21][O:22][CH2:23][CH3:24].[O:25]1[CH2:26][CH2:27][CH2:28][CH2:29]1>>[Br:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[N:8]([CH:12]1[CH2:17][CH2:18]1)[CH2:7][CH2:6][C:5]2([CH3:14])[CH3:15]

Participants

6

Reactant 5

HCID 259Bromide ionHCID 3283Diethyl EtherHCID 8028TetrahydrofuranHCID 225688836-Bromo-4,4-dimethyl-3,4-dihydroquinoline-1(2H)-carbaldehydeHCID 178461628HCID 178461628, compound

Product 1

HCID 225689356-Bromo-1-cyclopropyl-4,4-dimethyl-1,2,3,4-tetrahydroquinoline

Sources & evidence

ORD record
ord-dc2122a390104558a343c53f09ba8de5
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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