1,2-Dichloroethane → 1-(3-methoxy-4-nitrophenyl)-N,N-dimethylpiperidin-4-amine

HRID 836858Notes

Reaction equation

HRID 836858 reaction equation
[C:22]([OH:23])(=[O:24])[CH3:25].[C:26]([O:27][BH-:28]([O:29][C:30](=[O:31])[CH3:32])[O:33][C:34](=[O:35])[CH3:36])(=[O:37])[CH3:38].[CH3:19][NH:20][CH3:21].[CH3:1][O:2][c:3]1[cH:4][c:5]([N:12]2[CH2:13][CH2:14][C:15](=[O:18])[CH2:16][CH2:17]2)[cH:6][cH:7][c:8]1[N+:9](=[O:10])[O-:11].[Cl:40][CH2:41][CH2:42][Cl:43].[Na+:39].[OH2:44]>>[CH3:1][O:2][c:3]1[cH:4][c:5]([N:12]2[CH2:13][CH2:14][CH:15]([N:20]([CH3:19])[CH3:21])[CH2:16][CH2:17]2)[cH:6][cH:7][c:8]1[N+:9](=[O:10])[O-:11]

Participants

8

Reactant 7

HCID 111,2-DichloroethaneHCID 176Acetic AcidHCID 674DimethylamineHCID 923Sodium ionHCID 962WaterHCID 2724942TriacetoxyborohydrideHCID 259188571-(3-Methoxy-4-nitrophenyl)piperidin-4-one

Product 1

HCID 574161521-(3-methoxy-4-nitrophenyl)-N,N-dimethylpiperidin-4-amine

Sources & evidence

ORD record
ord-df7cc487243b478585e26669b9f19bbe
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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