3-Hydroxybenzyl alcohol → [3-(4-Fluorophenoxy)phenyl]methanol

HRID 836869Notes

Reaction equation

HRID 836869 reaction equation
[Br:10][c:11]1[cH:12][cH:13][c:14]([F:17])[cH:15][cH:16]1.[C:18](=[O:19])([O-:20])[O-:21].[CH3:35][N:36]1[CH2:37][CH2:38][N:39]([CH3:40])[C:41]1=[O:42].[K+:22].[K+:23].[OH2:43].[OH:1][CH2:2][c:3]1[cH:4][cH:5][cH:6][c:7]([OH:8])[cH:9]1.[n:24]1[c:25]2[c:26]([cH:27][cH:28][cH:29][c:30]2[OH:31])[cH:32][cH:33][cH:34]1>>[OH:1][CH2:2][c:3]1[cH:4][cH:5][cH:6][c:7]([O:8][c:11]2[cH:12][cH:13][c:14]([F:17])[cH:15][cH:16]2)[cH:9]1

Participants

8

Reactant 7

HCID 1023-Hydroxybenzyl alcoholHCID 813Potassium Cation2×HCID 962WaterHCID 19238-HydroxyquinolineHCID 66611,3-Dimethyl-2-imidazolidinoneHCID 99931-Bromo-4-fluorobenzeneHCID 19660Carbonate Ion

Product 1

HCID 10584901[3-(4-Fluorophenoxy)phenyl]methanol

Sources & evidence

ORD record
ord-ccbe8a3f91964eea825018d85c814c00
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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