Dichloromethane → 1-[1-(1-Methylpiperidin-4-yl)-1-phenylethyl]piperazine
Reaction equation
[CH2:36]([Cl:37])[Cl:38].[CH3:1][N:2]1[CH2:3][CH2:4][CH:5]([C:8]([CH3:9])([c:10]2[cH:11][cH:12][cH:13][cH:14][cH:15]2)[N:16]2[CH2:17][CH2:18][N:19]([C:22]([O:23][C:24]([CH3:25])([CH3:26])[CH3:27])=[O:28])[CH2:20][CH2:21]2)[CH2:6][CH2:7]1.[OH:29][C:30]([C:31]([F:32])([F:33])[F:34])=[O:35]>>[CH3:1][N:2]1[CH2:3][CH2:4][CH:5]([C:8]([CH3:9])([c:10]2[cH:11][cH:12][cH:13][cH:14][cH:15]2)[N:16]2[CH2:17][CH2:18][NH:19][CH2:20][CH2:21]2)[CH2:6][CH2:7]1Participants
4
Sources & evidence
- ORD record
- ord-4bd371a24a674b049f894d8cc7f821cf
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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