Hydrochloric Acid → N-methyl-N'-[3-(4-methyl-piperazin-1-ylmethyl)-phenyl]-pyrimidine-4,6-diamine

HRID 836961Notes

Reaction equation

HRID 836961 reaction equation
[CH3:10][N:11]1[CH2:12][CH2:13][N:14]([CH2:17][c:18]2[cH:19][c:20]([NH2:24])[cH:21][cH:22][cH:23]2)[CH2:15][CH2:16]1.[Cl:1][c:2]1[cH:3][c:4]([NH:8][CH3:9])[n:5][cH:6][n:7]1.[ClH:25].[O:26]1[CH2:27][CH2:28][O:29][CH2:30][CH2:31]1>>[c:2]1([NH:24][c:20]2[cH:19][c:18]([CH2:17][N:14]3[CH2:13][CH2:12][N:11]([CH3:10])[CH2:16][CH2:15]3)[cH:23][cH:22][cH:21]2)[cH:3][c:4]([NH:8][CH3:9])[n:5][cH:6][n:7]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 3094796-chloro-N-methylpyrimidin-4-amineHCID 64841863-[(4-Methylpiperazin-1-yl)methyl]aniline

Product 1

HCID 69180606N-methyl-N'-[3-(4-methyl-piperazin-1-ylmethyl)-phenyl]-pyrimidine-4,6-diamine

Sources & evidence

ORD record
ord-aefe8bbf83d041148c5723779bb19631
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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