Dichloromethane → trans-4-(6-Methoxy-quinolin-4-yloxymethyl)-cyclohexylamine
Reaction equation
[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([O:13][CH2:14][CH:15]3[CH2:16][CH2:17][CH:18]([NH:21][C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[CH2:19][CH2:20]3)[cH:7][cH:8][n:9][c:10]2[cH:11][cH:12]1.[Cl:36][CH2:37][Cl:38].[F:29][C:30]([F:31])([F:32])[C:33]([OH:34])=[O:35]>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([O:13][CH2:14][CH:15]3[CH2:16][CH2:17][CH:18]([NH2:21])[CH2:19][CH2:20]3)[cH:7][cH:8][n:9][c:10]2[cH:11][cH:12]1Participants
4
Sources & evidence
- ORD record
- ord-f7884aec6b0b4d71b3290a00339938ba
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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