Diethyl Ether → Ethyl 1-carbamothioylpiperidine-4-carboxylate

HRID 837141Notes

Reaction equation

HRID 837141 reaction equation
[CH2:21]([CH3:22])[O:23][C:24](=[O:25])[CH:26]1[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]1.[CH3:32][CH2:33][O:34][CH2:35][CH3:36].[CH:37]([Cl:38])([Cl:39])[Cl:40].[cH:1]1[c:2]2[c:14]([cH:15][cH:16][cH:17]1)-[c:9]1[c:8]([cH:13][cH:12][cH:11][cH:10]1)[CH:3]2[CH2:4][O:5][C:6](=[O:7])[N:18]=[C:19]=[S:20]>>[NH2:18][C:19](=[S:20])[N:29]1[CH2:28][CH2:27][CH:26]([C:24]([O:23][CH2:21][CH3:22])=[O:25])[CH2:31][CH2:30]1

Participants

5

Reactant 4

HCID 3283Diethyl EtherHCID 6212ChloroformHCID 70770Ethyl 4-piperidinecarboxylateHCID 4154759Fmoc isothiocyanate

Product 1

HCID 23076419Ethyl 1-carbamothioylpiperidine-4-carboxylate

Sources & evidence

ORD record
ord-f69df324c31c4006a582654d042e5ce3
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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