Dichloromethane → 2-[(2,4,5-Trifluorophenyl)methoxymethyl]-4-tritylsulfanylpyrrolidine
Reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH:9]([CH2:33][O:34][CH2:35][c:36]2[c:37]([F:44])[cH:38][c:39]([F:43])[c:40]([F:42])[cH:41]2)[CH2:10][CH:11]([S:13][C:14]([c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)([c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[CH2:12]1)([CH3:5])([CH3:6])[CH3:7].[Cl:52][CH2:53][Cl:54].[F:45][C:46]([F:47])([F:48])[C:49]([OH:50])=[O:51]>>[NH:8]1[CH:9]([CH2:33][O:34][CH2:35][c:36]2[c:37]([F:44])[cH:38][c:39]([F:43])[c:40]([F:42])[cH:41]2)[CH2:10][CH:11]([S:13][C:14]([c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)([c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[CH2:12]1Participants
4
Sources & evidence
- ORD record
- ord-817eae1614dc41498a7a6e92875cc4b6
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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