Trifluoroacetic acid → (1RS,2SR)-2-amino-1-(2-fluoropyridin-4-yl)-3-(3-(1,1,2,2-tetrafluoroethoxy)phenyl)-1-propanol
Reaction equation
[F:1][c:2]1[n:3][cH:4][cH:5][c:6]([CH:8]([CH:9]([CH2:10][c:11]2[cH:12][c:13]([O:17][C:18]([CH:19]([F:20])[F:21])([F:22])[F:23])[cH:14][cH:15][cH:16]2)[NH:24][C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[OH:32])[cH:7]1.[OH:33][C:34]([C:35]([F:36])([F:37])[F:38])=[O:39]>>[F:1][c:2]1[n:3][cH:4][cH:5][c:6]([CH:8]([CH:9]([CH2:10][c:11]2[cH:12][c:13]([O:17][C:18]([CH:19]([F:20])[F:21])([F:22])[F:23])[cH:14][cH:15][cH:16]2)[NH2:24])[OH:32])[cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-f9de83111d4046bf81c982daf40305a7
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…