Acetone → Tert-butyl 2-(2-(methoxymethoxy)-5-((4-propylpiperazin-1-yl)methyl)benzamido)-4-phenylbenzoate

HRID 837329Notes

Reaction equation

HRID 837329 reaction equation
[Br:7][CH2:8][c:9]1[cH:10][cH:11][c:12]([O:37][CH2:38][O:39][CH3:40])[c:13]([C:14](=[O:15])[NH:16][c:17]2[c:18]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[cH:26][cH:27][c:28](-[c:30]3[cH:31][cH:32][cH:33][cH:34][cH:35]3)[cH:29]2)[cH:36]1.[C:1](=[O:2])([O-:3])[O-:4].[CH2:43]([CH2:44][CH3:45])[N:46]1[CH2:47][CH2:48][NH:49][CH2:50][CH2:51]1.[CH3:52][C:53](=[O:54])[CH3:55].[ClH:41].[ClH:42].[K+:5].[K+:6]>>[CH2:8]([c:9]1[cH:10][cH:11][c:12]([O:37][CH2:38][O:39][CH3:40])[c:13]([C:14](=[O:15])[NH:16][c:17]2[c:18]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[cH:26][cH:27][c:28](-[c:30]3[cH:31][cH:32][cH:33][cH:34][cH:35]3)[cH:29]2)[cH:36]1)[N:49]1[CH2:48][CH2:47][N:46]([CH2:43][CH2:44][CH3:45])[CH2:51][CH2:50]1

Participants

7

Reactant 6

HCID 180AcetoneHCID 313Hydrochloric Acid2×HCID 813Potassium Cation2×HCID 19660Carbonate IonHCID 415812Piperazine, 1-propyl-, hydrochloride (1:2)HCID 66990849Tert-butyl 2-(5-(bromomethyl)-2-(methoxymethoxy)benzamido)-4-phenylbenzoate

Product 1

HCID 66990553Tert-butyl 2-(2-(methoxymethoxy)-5-((4-propylpiperazin-1-yl)methyl)benzamido)-4-phenylbenzoate

Sources & evidence

ORD record
ord-bfa472211f7a452bb046982905407f15
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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