Acetonitrile → N-(3-fluoropyridin-4-yl)-2,6-dichlorobenzamide

HRID 837463Notes

Reaction equation

HRID 837463 reaction equation
[CH3:32][C:33]#[N:34].[CH:9]([N:10]([CH2:11][CH3:12])[CH:13]([CH3:14])[CH3:15])([CH3:16])[CH3:17].[Cl:18][c:19]1[c:20]([C:21](=[O:22])[Cl:23])[c:24]([Cl:28])[cH:25][cH:26][cH:27]1.[Cl:29][CH2:30][Cl:31].[F:1][c:2]1[cH:3][n:4][cH:5][cH:6][c:7]1[NH2:8]>>[F:1][c:2]1[cH:3][n:4][cH:5][cH:6][c:7]1[NH:8][C:21]([c:20]1[c:19]([Cl:18])[cH:27][cH:26][cH:25][c:24]1[Cl:28])=[O:22]

Participants

6

Reactant 5

HCID 6342AcetonitrileHCID 6344DichloromethaneHCID 783922,6-Dichlorobenzoyl chlorideHCID 81531DiisopropylethylamineHCID 8171224-Amino-3-fluoropyridine

Product 1

HCID 59618080N-(3-fluoropyridin-4-yl)-2,6-dichlorobenzamide

Sources & evidence

ORD record
ord-848c2102024144feaa267713498d07e8
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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