Dichloromethane → 1-(3-(Pyridin-4-yl)-7a-(pyrrolidin-1-yl)-3a,4,7,7a-tetrahydroisoxazolo[4,5-c]pyridin-5(6H)-yl)ethanone

HRID 837586Notes

Reaction equation

HRID 837586 reaction equation
[CH2:25]([N:26]([CH2:27][CH3:28])[CH2:29][CH3:30])[CH3:31].[CH2:32]([Cl:33])[Cl:34].[N:1]1([C:6]2=[CH:7][CH2:8][N:9]([C:12]([CH3:13])=[O:14])[CH2:10][CH2:11]2)[CH2:2][CH2:3][CH2:4][CH2:5]1.[OH:15][N:16]=[C:17]([c:18]1[cH:19][cH:20][n:21][cH:22][cH:23]1)[Cl:24]>>[N:1]1([C:6]23[CH:7]([CH2:8][N:9]([C:12]([CH3:13])=[O:14])[CH2:10][CH2:11]2)[C:17]([c:18]2[cH:19][cH:20][n:21][cH:22][cH:23]2)=[N:16][O:15]3)[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 3014266N-hydroxy-4-pyridine-carboximidoyl chlorideHCID 141055951-(4-(Pyrrolidin-1-yl)-5,6-dihydropyridin-1(2H)-yl)ethanone

Product 1

HCID 686439771-(3-(Pyridin-4-yl)-7a-(pyrrolidin-1-yl)-3a,4,7,7a-tetrahydroisoxazolo[4,5-c]pyridin-5(6H)-yl)ethanone

Sources & evidence

ORD record
ord-8eabe5f75e3d452b9ff93f36be595fe2
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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