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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 837591Generated: October 29, 2026

Chloride → 5-{[2-Hydroxy-5-methoxy-2-(pentafluoroethyl)-4,4,7-trimethyl-1,2,3,4-tetrahydronaphthalen-1-yl]amino}-quinolin-2(1H)-one

https://huagongshe.com/reaction/837591

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorideHCID 312—
ReactantDichloromethaneHCID 6344—
ReactantTitanium cation (4+)HCID 114942—
Reactant5-Amino-1,2-dihydroquinolin-2-oneHCID 15719078—
Reactant4-(2-Methoxy-4-methylphenyl)-2-hydroxy-4-methyl-2-(pentafluoroethyl)pentanalHCID 17989161—
Product5-{[2-Hydroxy-5-methoxy-2-(pentafluoroethyl)-4,4,7-trimethyl-1,2,3,4-tetrahydronaphthalen-1-yl]amino}-quinolin-2(1H)-oneHCID 86599928—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-b1a80646d57d421f93131f49d9781e8e
Source noteTest data from https://doi.org/10.1039/C8SC04228D