Dichloromethane → Piperidin-3-ylmethyl-carbamic acid benzyl ester

HRID 837654Notes

Reaction equation

HRID 837654 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH:10]([CH2:14][NH:15][C:16](=[O:17])[O:18][CH2:19][c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[CH2:11][CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:33][CH2:34][Cl:35].[F:26][C:27]([F:28])([F:29])[C:30]([OH:31])=[O:32]>>[NH:8]1[CH2:9][CH:10]([CH2:14][NH:15][C:16](=[O:17])[O:18][CH2:19][c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[CH2:11][CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 451587943-(Benzyloxycarbonylaminomethyl)-piperidine-1-carboxylic Acid Tert-butyl Ester

Product 1

HCID 21104689Piperidin-3-ylmethyl-carbamic acid benzyl ester

Sources & evidence

ORD record
ord-4039466af8854fb384b151ec8bdd2e0d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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