Hydrochloric Acid → 2-Amino-2-(4-fluorophenyl)-1-quinolin-8-ylethanol

HRID 837679Notes

Reaction equation

HRID 837679 reaction equation
[CH2:30]([Cl:31])[Cl:32].[ClH:29].[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH:9]([c:10]2[cH:11][cH:12][cH:13][c:14]3[cH:15][cH:16][cH:17][n:18][c:19]23)[OH:20])[NH:21][C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[cH:6][cH:7]1.[O:33]1[CH2:34][CH2:35][O:36][CH2:37][CH2:38]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH:9]([c:10]2[cH:11][cH:12][cH:13][c:14]3[cH:15][cH:16][cH:17][n:18][c:19]23)[OH:20])[NH2:21])[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 312751,4-DioxaneHCID 86621954Tert-butyl [1-(4-fluorophenyl)-2-hydroxy-2-quinolin-8-ylethyl]carbamate

Product 1

HCID 675239562-Amino-2-(4-fluorophenyl)-1-quinolin-8-ylethanol

Sources & evidence

ORD record
ord-58379af974d84cd385dd70462c232c58
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…