Dichloromethane → 3-Ethoxy-2,6-difluoroaniline

HRID 837804Notes

Reaction equation

HRID 837804 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][c:8]1[c:9]([F:18])[c:10]([O:15][CH2:16][CH3:17])[cH:11][cH:12][c:13]1[F:14])([CH3:5])([CH3:6])[CH3:19].[Cl:27][CH2:28][Cl:29].[OH:20][C:21]([C:22]([F:23])([F:24])[F:25])=[O:26]>>[NH2:7][c:8]1[c:9]([F:18])[c:10]([O:15][CH2:16][CH3:17])[cH:11][cH:12][c:13]1[F:14]

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 69028840(3-Ethoxy-2,6-difluoro-phenyl)-carbamic acid tert-butyl ester

Product 1

HCID 184447123-Ethoxy-2,6-difluoroaniline

Sources & evidence

ORD record
ord-c6ce1e8dc400429db8ede9ff95eeae4b
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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