Dichloromethane → DL-norvaline

HRID 837811Notes

Reaction equation

HRID 837811 reaction equation
[C:1]([O:2][C:3]([CH3:4])([CH3:5])[CH3:6])(=[O:7])[NH:8][CH:9]([CH2:10][CH2:11][CH3:12])[C:13](=[O:14])[OH:15].[Cl:32][CH2:33][Cl:34].[F:25][C:26]([F:27])([F:28])[C:29]([OH:30])=[O:31].[NH2:16][CH:17]([CH2:18][CH:19]([CH3:20])[CH3:21])[C:22](=[O:23])[NH2:24]>>[NH2:16][CH:17]([CH2:18][CH:19]([CH3:20])[CH3:21])[C:22](=[O:23])[NH2:24].[NH2:8][CH:9]([CH2:10][CH2:11][CH3:12])[C:13](=[O:14])[OH:15]

Participants

6

Reactant 4

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 114616Pentanamide, 2-amino-4-methyl-HCID 3024332-(((Tert-butoxy)carbonyl)amino)pentanoic acid

Product 2

HCID 824DL-norvalineHCID 114616Pentanamide, 2-amino-4-methyl-

Sources & evidence

ORD record
ord-6e0b275596064a5593c6ceb88ea9019d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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