Sodium ion → Tert-butyl 2-[[4-[(4-chlorophenyl)methyl]phenoxy]methyl]pyrrolidine-1-carboxylate

HRID 838109Notes

Reaction equation

HRID 838109 reaction equation
[C:18]([CH3:19])([CH3:20])([CH3:21])[O:22][C:23](=[O:24])[N:25]1[CH:26]([CH2:30][O:31][S:32]([c:33]2[cH:34][cH:35][c:36]([CH3:37])[cH:38][cH:39]2)(=[O:40])=[O:41])[CH2:27][CH2:28][CH2:29]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][c:7]2[cH:8][cH:9][c:10]([OH:13])[cH:11][cH:12]2)[cH:14][cH:15]1.[H-:17].[Na+:16].[O:42]=[CH:43][N:44]([CH3:45])[CH3:46]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][c:7]2[cH:8][cH:9][c:10]([O:13][CH2:30][CH:26]3[N:25]([C:23]([O:22][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:24])[CH2:29][CH2:28][CH2:27]3)[cH:11][cH:12]2)[cH:14][cH:15]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 6228DimethylformamideHCID 166653HydrideHCID 13110388tert-Butyl 2-((tosyloxy)methyl)pyrrolidine-1-carboxylateHCID 131220024-[(4-Chlorophenyl)methyl]phenol

Product 1

HCID 69003417Tert-butyl 2-[[4-[(4-chlorophenyl)methyl]phenoxy]methyl]pyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-e771db9ee6ac4f35bbaa41a61ffb50b3
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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