Water → Butane-1-sulfonic acid 4-[2-(2,4-dichlorophenyl)-5-methyl-4-(piperidin-1-ylcarbamoyl)-imidazol-1-yl]phenyl ester

HRID 838147Notes

Reaction equation

HRID 838147 reaction equation
[CH2:38]([CH2:39][CH2:40][CH3:41])[S:42](=[O:43])(=[O:44])[Cl:45].[CH3:31][CH2:32][N:33]([CH2:34][CH3:35])[CH2:36][CH3:37].[Cl:47][CH2:48][Cl:49].[N:1]1([NH:7][C:8](=[O:9])[c:10]2[n:11][c:12](-[c:23]3[c:24]([Cl:30])[cH:25][c:26]([Cl:29])[cH:27][cH:28]3)[n:13](-[c:16]3[cH:17][cH:18][c:19]([OH:22])[cH:20][cH:21]3)[c:14]2[CH3:15])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[OH2:46]>>[N:1]1([NH:7][C:8](=[O:9])[c:10]2[n:11][c:12](-[c:23]3[c:24]([Cl:30])[cH:25][c:26]([Cl:29])[cH:27][cH:28]3)[n:13](-[c:16]3[cH:17][cH:18][c:19]([O:22][S:42]([CH2:38][CH2:39][CH2:40][CH3:41])(=[O:43])=[O:44])[cH:20][cH:21]3)[c:14]2[CH3:15])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

6

Reactant 5

HCID 962WaterHCID 6344DichloromethaneHCID 8471TriethylamineHCID 754301-Butanesulfonyl chlorideHCID 589650752-(2,4-Dichlorophenyl)-1-(4-hydroxyphenyl)-5-methyl-1H-imidazole-4-carboxylic acid piperidin-1-ylamide

Product 1

HCID 11706783Butane-1-sulfonic acid 4-[2-(2,4-dichlorophenyl)-5-methyl-4-(piperidin-1-ylcarbamoyl)-imidazol-1-yl]phenyl ester

Sources & evidence

ORD record
ord-ae096d9a87ea4dfa8a43796c8764bfef
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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