Tetrahydrofuran → 1-[6-(4-Bromo-2-chloro-phenylamino)-7-fluoro-3-methyl-3H-benzoimidazol-5-yl]-2-methoxymethoxy-ethanol

HRID 838171Notes

Reaction equation

[Br:24][c:25]1[cH:26][c:27]([Cl:45])[c:28]([NH:31][c:32]2[c:33]([CH:43]=[O:44])[cH:34][c:35]3[c:36]([n:37][cH:38][n:39]3[CH3:40])[c:41]2[F:42])[cH:29][cH:30]1.[CH2:1]([Sn:2]([CH2:3][CH2:4][CH2:5][CH3:11])([CH2:6][O:7][CH2:8][O:9][CH3:10])[CH2:12][CH2:13][CH2:14][CH3:15])[CH2:16][CH2:17][CH3:18].[CH2:46]1[O:47][CH2:48][CH2:49][CH2:50]1.[CH3:19][CH2:20][CH2:21][CH2:22][Li:23]>>[CH2:6]([O:7][CH2:8][O:9][CH3:10])[CH:43]([c:33]1[c:32]([NH:31][c:28]2[c:27]([Cl:45])[cH:26][c:25]([Br:24])[cH:30][cH:29]2)[c:41]([F:42])[c:36]2[c:35]([cH:34]1)[n:39]([CH3:40])[cH:38][n:37]2)[OH:44]