Chloride → 1-(2'-Fluoro[1,1'-biphenyl]-4-yl)ethanone

HRID 838238Notes

Reaction equation

HRID 838238 reaction equation
[Al+3:2].[CH2:23]([Cl:24])[Cl:25].[CH3:18][C:19]([Cl:20])=[O:21].[Cl-:1].[Cl-:3].[Cl-:4].[F:5][c:6]1[c:7](-[c:12]2[cH:13][cH:14][cH:15][cH:16][cH:17]2)[cH:8][cH:9][cH:10][cH:11]1.[OH2:22]>>[F:5][c:6]1[c:7](-[c:12]2[cH:13][cH:14][c:15]([C:19]([CH3:18])=[O:21])[cH:16][cH:17]2)[cH:8][cH:9][cH:10][cH:11]1

Participants

7

Reactant 6

HCID 312Chloride3×HCID 962WaterHCID 6344DichloromethaneHCID 6367Acetyl chlorideHCID 675792-FluorobiphenylHCID 104727Aluminum Cation

Product 1

HCID 676621-(2'-Fluoro[1,1'-biphenyl]-4-yl)ethanone

Sources & evidence

ORD record
ord-f53412299cae454b8ba8f32ba48b4919
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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