Bromide ion → (3-Bromomethyl-5-fluoro-phenyl)-(4-methoxy-benzyl)-amine

HRID 838332Notes

Reaction equation

HRID 838332 reaction equation
[Br-:20].[Br-:21].[Cl:41][CH2:42][Cl:43].[F:1][c:2]1[cH:3][c:4]([CH2:18][OH:19])[cH:5][c:6]([NH:8][CH2:9][c:10]2[cH:11][cH:12][c:13]([O:16][CH3:17])[cH:14][cH:15]2)[cH:7]1.[c:22]1([P:23]([c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[cH:36][cH:37][cH:38][cH:39][cH:40]1>>[F:1][c:2]1[cH:3][c:4]([CH2:18][Br:20])[cH:5][c:6]([NH:8][CH2:9][c:10]2[cH:11][cH:12][c:13]([O:16][CH3:17])[cH:14][cH:15]2)[cH:7]1

Participants

5

Reactant 4

HCID 259Bromide ion2×HCID 6344DichloromethaneHCID 11776TriphenylphosphineHCID 59184687[3-Fluoro-5-(4-methoxy-benzylamino)-phenyl]-methanol

Product 1

HCID 59184728(3-Bromomethyl-5-fluoro-phenyl)-(4-methoxy-benzyl)-amine

Sources & evidence

ORD record
ord-1577f3651da346419aa879c59a0dc503
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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