Hydrochloric Acid → Tert-butyl 2-[[1-(methoxymethyl)-7-phenoxy-4-phenylmethoxyisoquinoline-3-carbonyl]amino]propanoate

HRID 838473Notes

Reaction equation

HRID 838473 reaction equation
[C:33]([CH3:34])([CH3:35])([CH3:36])[O:37][C:38]([CH:39]([NH2:40])[CH3:41])=[O:42].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([C:29](=[O:30])[OH:31])[n:11][c:12]([CH2:26][O:27][CH3:28])[c:13]2[cH:14][c:15]([O:19][c:20]3[cH:21][cH:22][cH:23][cH:24][cH:25]3)[cH:16][cH:17][c:18]12.[Cl:43][CH2:44][Cl:45].[ClH:32]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([C:29](=[O:30])[NH:40][CH:39]([C:38]([O:37][C:33]([CH3:34])([CH3:35])[CH3:36])=[O:42])[CH3:41])[n:11][c:12]([CH2:26][O:27][CH3:28])[c:13]2[cH:14][c:15]([O:19][c:20]3[cH:21][cH:22][cH:23][cH:24][cH:25]3)[cH:16][cH:17][c:18]12

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 4351123Tert-butyl 2-aminopropanoateHCID 667128304-Benzyloxy-1-methoxymethyl-7-phenoxy-isoquinoline-3-carboxylic acid

Product 1

HCID 66712879Tert-butyl 2-[[1-(methoxymethyl)-7-phenoxy-4-phenylmethoxyisoquinoline-3-carbonyl]amino]propanoate

Sources & evidence

ORD record
ord-d277380123e54fe593ed1d1ac9286840
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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