Hydrochloric Acid → 3-[1-(3-hydroxy-2,2-dimethylpropyl)piperidin-4-yl]-2H-isoquinolin-1-one

HRID 838556Notes

Reaction equation

HRID 838556 reaction equation
[Br:19][CH2:20][C:21]([CH2:22][OH:23])([CH3:24])[CH3:25].[ClH:1].[NH:2]1[CH2:3][CH2:4][CH:5]([c:8]2[nH:9][c:10](=[O:18])[c:11]3[cH:12][cH:13][cH:14][cH:15][c:16]3[cH:17]2)[CH2:6][CH2:7]1>>[N:2]1([CH2:20][C:21]([CH2:22][OH:23])([CH3:24])[CH3:25])[CH2:3][CH2:4][CH:5]([c:8]2[nH:9][c:10](=[O:18])[c:11]3[cH:12][cH:13][cH:14][cH:15][c:16]3[cH:17]2)[CH2:6][CH2:7]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 1425013-Bromo-2,2-dimethyl-1-propanolHCID 229311823-(Piperidin-4-yl)-1,2-dihydroisoquinolin-1-one

Product 1

HCID 103135603-[1-(3-hydroxy-2,2-dimethylpropyl)piperidin-4-yl]-2H-isoquinolin-1-one

Sources & evidence

ORD record
ord-1083feb5b4784f969196daa10206b01b
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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