Tetrahydrofuran → (9-(3-(1-Fluoro-2-hydroxyethyl)benzyl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)(2-isopropylthiazol-4-yl)methanone

HRID 838557노트

반응식

[C:1]([Si:2]([CH3:3])([CH3:4])[O:6][CH2:7][CH:8]([F:9])[c:10]1[cH:11][c:12]([CH2:13][N:14]2[CH2:15][CH2:16][C:17]3([CH2:18][N:19]([C:23](=[O:24])[c:25]4[n:26][c:27]([CH:30]([CH3:31])[CH3:32])[s:28][cH:29]4)[CH2:20][CH2:21][O:22]3)[CH2:33][CH2:34]2)[cH:35][cH:36][cH:37]1)([CH3:5])([CH3:38])[CH3:39].[CH2:58]1[O:59][CH2:60][CH2:61][CH2:62]1.[CH3:41][CH2:42][CH2:43][CH2:44][N+:45]([CH2:46][CH2:47][CH2:48][CH3:49])([CH2:50][CH2:51][CH2:52][CH3:53])[CH2:54][CH2:55][CH2:56][CH3:57].[F-:40]>>[OH:6][CH2:7][CH:8]([F:9])[c:10]1[cH:11][c:12]([CH2:13][N:14]2[CH2:15][CH2:16][C:17]3([CH2:18][N:19]([C:23](=[O:24])[c:25]4[n:26][c:27]([CH:30]([CH3:31])[CH3:32])[s:28][cH:29]4)[CH2:20][CH2:21][O:22]3)[CH2:33][CH2:34]2)[cH:35][cH:36][cH:37]1