Dichloromethane → Tert-butyl 4-acetylpiperazine-1-carboxylate

HRID 838725Notes

Reaction equation

HRID 838725 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]1.[CH3:14][CH2:15][N:16]([CH2:17][CH3:18])[CH2:19][CH3:20].[CH3:21][C:22]([Cl:23])=[O:24].[Cl:25][CH2:26][Cl:27]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([C:22]([CH3:21])=[O:24])[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 6367Acetyl chlorideHCID 8471TriethylamineHCID 143452tert-Butyl piperazine-1-carboxylate

Product 1

HCID 22707023Tert-butyl 4-acetylpiperazine-1-carboxylate

Sources & evidence

ORD record
ord-f9b9bc4acdb2450aabc0fc16898273b7
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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