Triphenylphosphine → 2-amino-4-(1-fluoro-ethyl)-5-(2-isopropyl-2H-pyrazol-3-yl)-benzoic acid methyl ester

HRID 838741Notes

Reaction equation

[CH3:1][O:2][C:3]([c:4]1[c:5]([NH2:14])[cH:6][c:7]([CH:11]([CH3:12])[F:13])[c:8]([I:10])[cH:9]1)=[O:15].[CH:16]([CH3:17])([CH3:18])[n:19]1[n:20][cH:21][cH:22][c:23]1[Sn:24]([CH2:25][CH2:26][CH2:27][CH3:28])([CH2:29][CH2:30][CH2:31][CH3:32])[CH2:33][CH2:34][CH2:35][CH3:36].[O:37]1[CH2:38][CH2:39][O:40][CH2:41][CH2:42]1.[Pd:43]([Cl:44])[Cl:45].[c:46]1([P:47]([c:48]2[cH:49][cH:50][cH:51][cH:52][cH:53]2)[c:54]2[cH:55][cH:56][cH:57][cH:58][cH:59]2)[cH:60][cH:61][cH:62][cH:63][cH:64]1.[c:65]1([P:66]([c:67]2[cH:68][cH:69][cH:70][cH:71][cH:72]2)[c:73]2[cH:74][cH:75][cH:76][cH:77][cH:78]2)[cH:79][cH:80][cH:81][cH:82][cH:83]1>>[CH3:1][O:2][C:3]([c:4]1[c:5]([NH2:14])[cH:6][c:7]([CH:11]([CH3:12])[F:13])[c:8](-[c:23]2[n:19]([CH:16]([CH3:17])[CH3:18])[n:20][cH:21][cH:22]2)[cH:9]1)=[O:15]