Potassium Carbonate → HCID 70620859, compound

HRID 838792Notes

Reaction equation

HRID 838792 reaction equation
[C:1]1([N:7]2[C:11](=[O:12])[CH:10]([CH2:13][CH2:14][S:15][CH3:16])[NH:9][C:8]2=[O:17])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.S([O-])(O[CH3:22])(=O)=O.C(=O)([O-])[O-].[K+].[K+]>CC(C)=O>[CH3:22][N:9]1[CH:10]([CH2:13][CH2:14][S:15][CH3:16])[C:11](=[O:12])[N:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[C:8]1=[O:17]

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 912035-[2-(Methylthio)ethyl]-3-phenyl-2,4-imidazolidinedioneHCID 4694097Methyl sulfate(1-)

Product 1

HCID 70620859HCID 70620859, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent2×

Procedure

A solution in acetone of 250 g (1 mole) of 3-phenyl-5-methylthioethyl hydantoin (compound no. 27) and 126 g (1 mole) of methyl sulphate is heated under reflux for 8 hours, accompanied by the addition with stirring of 138 g (1 mole) of potassium carbonate. The concentration of the acetone solution is between 0.5 and 1 mole per liter. On completion of the reaction, the potassium salts are separated by filtration and the acetone eliminated by evaporation. The residue crystallises on cooling. It can be recrystallised from methanol.

Workup

  1. temperatureunder reflux for 8 hours
  2. additionaccompanied by the addition
  3. customOn completion of the reaction
  4. customthe potassium salts are separated by filtration
  5. customthe acetone eliminated by evaporation
  6. customThe residue crystallises
  7. temperatureon cooling
  8. customIt can be recrystallised from methanol

Sources & evidence

ORD record
ord-0ba1a3fc83d648aa9c832f5f46dcd030
Source dataset
uspto-grants-1978_06
Patent number
US04093444

Reaction notes

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