Hydrochloric Acid → 1,2,3-Propanetricarboxylic acid, 1-phosphono-

Participants

Reaction Steps

The ester thus obtained and 100 cc of concentrated hydrochloric acid were heated to boiling temperature (which increased from 75° to 105° C) while methyl chloride and methanol originating from the hydrolysis were distilled off. After the hydrolysis was complete, the reaction solution was evaporated under vacuum to dryness (maximum base temperature = 120° C) and diluted with water so as to obtain a solution of 50% strength.

Provenance & Evidence