Hydrazine hydrate (1:1) → HCID 20325477, compound

HRID 838979Notes

Reaction equation

HRID 838979 reaction equation
[OH:1][CH:2]([CH2:16][NH:17][CH:18]([CH3:20])[CH3:19])[CH2:3][O:4][C:5]1[CH:14]=[C:13]2[C:8]([CH:9]=[N:10][NH:11][C:12]2=S)=[CH:7][CH:6]=1.O.[NH2:22][NH2:23]>>[OH:1][CH:2]([CH2:16][NH:17][CH:18]([CH3:20])[CH3:19])[CH2:3][O:4][C:5]1[CH:14]=[C:13]2[C:8]([CH:9]=[N:10][N:11]=[C:12]2[NH:22][NH2:23])=[CH:7][CH:6]=1

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 20325512HCID 20325512, compound

Product 1

HCID 20325477HCID 20325477, compound

Procedure

7-(2-Hydroxy-3-isopropylaminopropoxy)-1(2H)-phthalazinethione was reacted with hydrazine hydrate in a similar manner to that described in Example 1(viii) to give 7-(2-hydroxy-3-isopropylaminopropoxy)-1-hydrazinophthalazine which was isolated as its hydrochloride m.p. 249°-253° (decomposition).

Sources & evidence

ORD record
ord-778c28de1626415689f9b0f2d6d54322
Source dataset
uspto-grants-1978_06
Patent number
US04093725

Reaction notes

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