Sodium Pyrosulfite → HCID 135729097, compound

Participants

Reaction Steps

Sodium hypochlorite solution (10% w/v chlorine, 175 ml) was added to a stirred solution of 7-hydroxy-1(2H)-phthalazinone (10 g, 0.062 mol) in aqueous sodium hydroxide (2N, 140 ml), and the stirring was continued for two hours. An excess of sodium metabisulphite was added to the reaction mixture, and the precipitate was recrystallised from ethanol to give 6-chloro-7-hydroxy-1(2H)-phthalazinone, m.p. > 340° (decomp), which was purified via the acetyl derivative m.p. 190°-192° as described in Example 4(i).

Provenance & Evidence