4-{[(2,2-Dichlorocyclopropyl)methyl]sulfanyl}-2-nitroaniline → HCID 20532837, compound

HRID 838994Notes

Reaction equation

HRID 838994 reaction equation
[Cl:1][C:2]1([Cl:17])[CH2:4][CH:3]1[CH2:5][S:6][C:7]1[CH:13]=[CH:12][C:10]([NH2:11])=[C:9]([N+:14]([O-])=O)[CH:8]=1>C(O)C.O=[Pt]=O>[Cl:17][C:2]1([Cl:1])[CH2:4][CH:3]1[CH2:5][S:6][C:7]1[CH:13]=[CH:12][C:10]([NH2:11])=[C:9]([NH2:14])[CH:8]=1

Participants

4

Reactant 1

HCID 205328394-{[(2,2-Dichlorocyclopropyl)methyl]sulfanyl}-2-nitroaniline

Product 1

HCID 20532837HCID 20532837, compound

Reagents, catalysts & solvents 2

HCID 345198Adams' catalystCatalystHCID 702EthanolSolvent

Procedure

A mixture of 8.8 g (0.03 mole) of 4-[(2,2-dichlorocyclopropyl)methyl]thio-2-nitroaniline and 0.6 g of PtO2 in 200 ml of absolute ethanol is reduced on the Parr hydrogenator at 50 psi until the theoretical amount of H2 is absorbed. The mixture is filtered and the solvent is removed in vacuo to yield a dark oil.

Workup

  1. customis absorbed
  2. filtrationThe mixture is filtered
  3. customthe solvent is removed in vacuo
  4. customto yield a dark oil

Sources & evidence

ORD record
ord-c95af21799184039981f22fc33207576
Source dataset
uspto-grants-1978_06
Patent number
US04093732

Reaction notes

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