Ammonia → HCID 54425803, compound

HRID 839065Notes

Reaction equation

HRID 839065 reaction equation
[F:1][C:2]([F:26])([F:25])[C:3]([C:9]1[CH:14]=[CH:13][C:12]([NH:15][C:16](=O)[O:17]C2C=CC=CC=2)=[CH:11][CH:10]=1)([OH:8])[C:4]([F:7])([F:6])[F:5].[NH3:27]>O>[F:26][C:2]([F:1])([F:25])[C:3]([C:9]1[CH:14]=[CH:13][C:12]([NH:15][C:16]([NH2:27])=[O:17])=[CH:11][CH:10]=1)([OH:8])[C:4]([F:6])([F:7])[F:5]

Participants

4

Reactant 2

HCID 222AmmoniaHCID 53761679HCID 53761679, compound

Product 1

HCID 54425803HCID 54425803, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
0 °C

Procedure

Combine 6.0 g (16 mmole) of phenyl N-[4-(hexafluoro-2-hydroxy-2-propyl)phenyl]carbamate (Example 12) and 65 ml of NH3 saturated ethanol. After 1/2 hour, pour the reaction mixture into 150 ml of H2O. Concentrate, cool to 0° C and filter off the white solid. Obtain 5.5 g of N-[4-(hexafluoro-2-hydroxy-2-propyl)phenyl]urea; m.p. 181°-183° C.

Workup

  1. concentrationConcentrate
  2. filtrationfilter off the white solid

Sources & evidence

ORD record
ord-51dfe91fa9b34ef28142dd38c0c1f29a
Source dataset
uspto-grants-1978_06
Patent number
US04093742

Reaction notes

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