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HRID839069

反应详情

EQUATION

反应方程式

HRID 839069 的结构方程式

REACTANTS

反应物

2
结构：N
HCID222

Ammonia gas

H3N

结构：CN(C(=O)Cl)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1
HCID54019979

未命名化合物

PRODUCTS

生成物

1
结构：CN(C(N)=O)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1
HCID54046793

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCOCC
溶剂HCID3283

Diethyl Ether

C4H10O

PROCEDURE

实验过程

Saturate with NH3 a solution of 6.7 g (20 mmole) N-methyl-N-[4-(hexafluoro-2-hydroxy-2-propyl)phenyl]carbamyl chloride in 200 ml Et2O. After 24 hours, wash the Et2O with water, then 1N HCl. Dry, concentrate and recrystallize the solid from ether-hexane to give 5.0 g white solid; m.p. 181°-184°.

WORKUP

后处理

  1. washwash the Et2O with water
  2. customDry
  3. concentrationconcentrate
  4. customrecrystallize the solid from ether-hexane