Glycerol → HCID 21900766, compound

HRID 839093Notes

Reaction equation

HRID 839093 reaction equation
[OH:1][CH2:2][CH:3]([CH2:5][OH:6])[OH:4].[C:7]([OH:11])(=O)[CH2:8][SH:9].C1(C)C=C[C:15]([S:18](O)(=O)=O)=[CH:14]C=1.C1(C)C=CC=CC=1.[OH2:30]>>[C:14]([O:1][CH2:2][CH:3]([CH2:5][OH:6])[O:4][C:7](=[O:11])[CH2:8][SH:9])(=[O:30])[CH2:15][SH:18]

Participants

6

Reactant 5

HCID 753GlycerolHCID 962WaterHCID 1133Thioglycolic AcidHCID 1140TolueneHCID 6101p-Toluenesulfonic acid

Product 1

HCID 21900766HCID 21900766, compound

Procedure

A reaction mixture of 20 g. of glycerol, 40 g. of thioglycolic acid, 0.3 g. of p-toluenesulfonic acid, and 30 g. of toluene was refluxed in a nitrogen atmosphere, for 1 hr. at 108°-117° C and 1 hr. at 117° C to 120° C. 7.6 g. of water of condensation were collected, compared to an expected 7.8 g. The reaction mixture was stripped to a pot temperature of 120° C at 5 torr. The residual product was a clear and colourless liquid.

Workup

  1. additionA reaction mixture of 20 g
  2. customat 108°-117° C
  3. custom1 hr
  4. customat 117° C to 120° C
  5. customwere collected
  6. customwas stripped to a pot temperature of 120° C at 5 torr

Sources & evidence

ORD record
ord-4017ad61e6d24b1e91886fbdb556e71a
Source dataset
uspto-grants-1978_06
Patent number
US04093780

Reaction notes

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