反应详情

温度

0 °C

Stir together 18 g of 3-(5-nitro-2-furyl)-1H-pyrazole-4-carboxaldehyde, 6.95 of hydroxylamine hydrochloride and 8.2 g of sodium acetate in 70 ml of water for 1.5 hours at 70° C. Cool the resulting admixture slowly to 0° C. Separate the formed precipitate by vacuum filtration and wash the residue with several portions of ice-cold water to obtain a 97% yield of 3-(5-nitro-2-furyl)-1H-pyrazole-4-carboxaldehydeoxime [m.p. 233° to 235° C (with decomposition)].

1. customSeparate the formed precipitate
2. filtrationby vacuum filtration
3. washwash the residue with several portions of ice-cold water