Acetic Anhydride → HCID 54374358, compound

HRID 839209Notes

Reaction equation

HRID 839209 reaction equation
[CH3:1][N:2]1[CH:6]=[C:5]([CH:7]=[N:8][OH:9])[C:4]([C:10]2[O:11][C:12]([N+:15]([O-:17])=[O:16])=[CH:13][CH:14]=2)=[N:3]1.[C:18](OC(=O)C)(=[O:20])[CH3:19]>C1C=CC=CC=1>[C:18]([O:9][N:8]=[CH:7][C:5]1[C:4]([C:10]2[O:11][C:12]([N+:15]([O-:17])=[O:16])=[CH:13][CH:14]=2)=[N:3][N:2]([CH3:1])[CH:6]=1)(=[O:20])[CH3:19]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 54488696N-{[1-Methyl-3-(5-nitrofuran-2-yl)-1H-pyrazol-4-yl]methylidene}hydroxylamine

Product 1

HCID 54374358HCID 54374358, compoundYield 83%

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

Stir together 2.5 g of 1-methyl-3-(5-nitro-2-furyl)pyrazole-4-carboxaldehydeoxime, 1.27 g of acetic anhydride and 10 ml of benzene for 2 hours at from 80° to 85° C. Cool the resulting solution and vacuum filter to obtain 1-methyl-3-(5-nitro-2-furyl)pyrazole-4-carboxaldehyde-(O-acetyloxime) [m.p. 192° to 197° C (with decomposition) from toluene] with a yield of 83%.

Workup

  1. temperatureCool the resulting solution and vacuum
  2. filtrationfilter

Sources & evidence

ORD record
ord-24d068d3ef884ed8ab982ebd90ebe890
Source dataset
uspto-grants-1978_06
Patent number
US04093812

Reaction notes

Loading…