Ethanol → HCID 54261027, compound

HRID 839211Notes

Reaction equation

HRID 839211 reaction equation
[CH3:1][N:2]1[CH:6]=[C:5]([CH:7]=O)[C:4]([C:9]2[O:10][C:11]([N+:14]([O-:16])=[O:15])=[CH:12][CH:13]=2)=[N:3]1.[CH3:17][N:18]([CH3:20])[NH2:19].C(O)C>C(O)(=O)C.O>[CH3:17][N:18]([CH3:20])[N:19]=[CH:7][C:5]1[C:4]([C:9]2[O:10][C:11]([N+:14]([O-:16])=[O:15])=[CH:12][CH:13]=2)=[N:3][N:2]([CH3:1])[CH:6]=1

Participants

6

Reactant 3

HCID 702EthanolHCID 59761,1-DimethylhydrazineHCID 203259351-Methyl-3-(5-nitrofuran-2-yl)-1H-pyrazole-4-carbaldehyde

Product 1

HCID 54261027HCID 54261027, compoundYield 96%

Reagents, catalysts & solvents 2

HCID 176Acetic AcidCatalystHCID 962WaterSolvent

Procedure

Stir together 2 g of 1-methyl-3-(5-nitro-2-furyl)pyrazole-4-carboxaldehyde, 0.65 g of N,N-dimethylhydrazine, 2 drops of glacial acetic acid and 30 ml of ethanol for 4 hours at room temperature. Add 30 ml of water dropwise thereto to obtain a 96% yield of 1-methyl-3-(5-nitro-2-furyl)pyrazole-4-carboxaldehyde-dimethylhydrazone [m.p. 164° to 165° C].

Sources & evidence

ORD record
ord-6cd01db5e92846a5821cbab57722f2cb
Source dataset
uspto-grants-1978_06
Patent number
US04093812

Reaction notes

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