反应详情

Stir together 6.7 g of 1-methoxycarbonyl-3-(5-nitro-2-furyl)pyrazole-4-carboxaldehyde, 2.85 g of 4-aminomorpholine and 1.6 ml of glacial acetic acid in 125 ml of methanol for 3 hours at room temperature. Cool the resulting admixture on ice to produce a precipitate. Vacuum filter the precipitate and then suspend it once more in ethanol to obtain a 70% yield of 4-[1-methoxycarbonyl-3-(5-nitro-2-furyl)pyrazol-4-ylmethyleneamino]morpholine [m.p. 184° C (with decomposition)].

1. temperatureCool the resulting admixture on ice
2. customto produce a precipitate
3. filtrationVacuum filter the precipitate