HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → 4-[1-Methoxycarbonyl-3-(5-nitro-2-furyl)pyrazol-4-ylmethyleneamino]morpholine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | N-Aminomorpholine | HCID 20315 | — |
| Reactant | 1-Methoxycarbonyl-3-(5-nitro-2-furyl)pyrazole-4-carboxaldehyde | HCID 20325942 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-[1-Methoxycarbonyl-3-(5-nitro-2-furyl)pyrazol-4-ylmethyleneamino]morpholine | HCID 70619801 | 70% |
Reaction Steps
Stir together 6.7 g of 1-methoxycarbonyl-3-(5-nitro-2-furyl)pyrazole-4-carboxaldehyde, 2.85 g of 4-aminomorpholine and 1.6 ml of glacial acetic acid in 125 ml of methanol for 3 hours at room temperature. Cool the resulting admixture on ice to produce a precipitate. Vacuum filter the precipitate and then suspend it once more in ethanol to obtain a 70% yield of 4-[1-methoxycarbonyl-3-(5-nitro-2-furyl)pyrazol-4-ylmethyleneamino]morpholine [m.p. 184° C (with decomposition)].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04093812 |
| Source dataset | uspto-grants-1978_06 |
| ORD ID | ord-c2fadde68f684bb28d53fd13f39c1486 |
| Source note | uspto-grants-1978_06 |