HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → 1-Methyl-3-(5-nitrofuran-2-yl)-1H-pyrazole-4-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 1-Methyl-3-(5-nitrofuran-2-yl)-1H-pyrazole-4-carbonitrile | HCID 20326043 | — |
| Product | 1-Methyl-3-(5-nitrofuran-2-yl)-1H-pyrazole-4-carboxamide | HCID 20326060 | 97% |
Reaction Steps
While cooling and stirring 80 ml of concentrated sulfuric acid at room temperature, add 40 g of 1-methyl-3-(5-nitro-2-furyl)pyrazole-4-carbonitrile thereto. Then stir the resulting mixture for 21 hours at room temperature. Pour thus-obtained solution onto ice for a 97% yield of 1-methyl-3-(5-nitro-2-furyl)pyrazole-4-carboxamide [m.p. 251° to 252.5° C].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04093812 |
| Source dataset | uspto-grants-1978_06 |
| ORD ID | ord-44ad9a5e28a44eef93c5a6469008066a |
| Source note | uspto-grants-1978_06 |