Hydrochloric Acid → HCID 20324112, compound

HRID 839269Notes

Reaction equation

HRID 839269 reaction equation
[C:1]([CH2:3][C:4]1[CH:9]=[CH:8][C:7]([NH:10][C:11](=[O:20])[O:12][CH2:13][C:14]2[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=2)=[CH:6][CH:5]=1)#[N:2].[ClH:21]>CC(C)=O>[ClH:21].[C:1]([CH2:3][C:4]1[CH:9]=[CH:8][C:7]([NH:10][C:11](=[O:20])[O:12][CH2:13][C:14]2[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=2)=[CH:6][CH:5]=1)#[N:2]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 20324109Carbamic acid, [4-(cyanomethyl)phenyl]-, 3-pyridinylmethyl ester

Product 1

HCID 20324112HCID 20324112, compoundYield 93.5%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

To a solution of 3-pyridylmethyl N-(4-cyanomethylphenyl)carbamate (5 g., 0.0187 mole) in 300 ml. of acetone was added an excess of hydrogen chloride in a steady stream. A white suspension formed and was filtered off to give 5.3 g. of solid melting at 215°-216° C. This was a 93.5% yield of 3-pyridylmethyl N-(4-cyanomethylphenyl)carbamate hydrochloride.

Workup

  1. customA white suspension formed
  2. filtrationwas filtered off
  3. customto give 5.3 g

Sources & evidence

ORD record
ord-5bd734d5866e446389b7b0248ae3319a
Source dataset
uspto-grants-1978_06
Patent number
US04094875

Reaction notes

Loading…