HCID 20324274, compound → HCID 15328860, compound

HRID 839309Notes

Reaction equation

HRID 839309 reaction equation
[Br:1][C:2]1[CH:17]=[CH:16][C:5]([C:6]([CH:14]=[CH2:15])([OH:13])[C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[CH:4][CH:3]=1>[Pd].C1C=CC=CC=1>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([CH2:14][CH3:15])([OH:13])[C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[CH:16][CH:17]=1

Participants

4

Reactant 1

HCID 20324274HCID 20324274, compound

Product 1

HCID 15328860HCID 15328860, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 241BenzeneSolvent

Procedure

0.6 g. of 10% palladium-on-carbon and added to a solution of 29 g. of 4-bromo-α-vinyl-benzhydrol in 300 ml. of benzene, and the mixture is hydrogenated at room temperature under atmospheric pressure. After the uptake of the calculated amount of hydrogen the catalyst is filtered off, and the benzene is evaporated from the clear filtrate under reduced pressure. 25 g. of clear, viscous oil, boiling at 140° C (0.8 mmHG.) are obtained as residue.

Workup

  1. customis hydrogenated at room temperature under atmospheric pressure
  2. filtrationAfter the uptake of the calculated amount of hydrogen the catalyst is filtered off
  3. customthe benzene is evaporated from the clear filtrate under reduced pressure
  4. customof clear, viscous oil, boiling at 140° C (0.8 mmHG.) are obtained as residue

Sources & evidence

ORD record
ord-a3e844e471ee47c49bb1fc58611001de
Source dataset
uspto-grants-1978_06
Patent number
US04094908

Reaction notes

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